Medical Dictionary

Adie's syndrome

noun Ad·ie's syndrome \ˈā-dēz-\
variants: or

Adie syndrome


Medical Definition of Adie's syndrome

  1. :  a neurological disorder that is characterized especially by an abnormally dilated pupil, absent or diminished light reflexes of the eye, abnormal visual accommodation, and usually impaired reflex activity of the arms or legs, that typically occurs between the ages of 20 to 50 and most commonly affects women, and that is caused by damage to the ciliary ganglion often thought to result from a viral or bacterial infection A necropsy is reported on a patient with Adie's syndrome, in which the pathological basis of the pupillary abnormality is clearly shown to be neuronal degeneration in the ciliary ganglion.—D. G. F. Harriman and Hugh Garland, Brain, September 1968—called also Holmes-Adie syndrome

Biographical Note for adie's syndrome


\ˈā-dē\play ,

William John

(1886–1935), British neurologist. Adie was on the staff at Charing Cross Hospital, Royal London Ophthalmic Hospital, and London's National Hospital for Nervous Diseases. He described the neurological disorder now known as Adie's syndrome in 1931. He is also remembered for his description of a kind of idiopathic narcolepsy and for the chapters on diseases of the nervous system that he contributed to medical textbooks.

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