histone deacetylase

noun

Medical Definition of histone deacetylase

: an enzyme that catalyzes the hydrolysis of acetyl groups from histone Histones are proteins that regulate DNA packing, and histone deacetylases are enzymes that control the way those proteins work. One of their effects is to keep HIV genes switched off.The Economist, 23 July 2011

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“Histone deacetylase.” Merriam-Webster.com Medical Dictionary, Merriam-Webster, https://www.merriam-webster.com/medical/histone%20deacetylase. Accessed 27 Oct. 2020.

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