heavy chain

noun

: either of the two larger of the four polypeptide chains comprising antibodies compare light chain

Examples of heavy chain in a Sentence

Recent Examples on the Web
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Kunzweiler gestured toward the defense table, where Wilkens sat in a striped orange jail jumpsuit, her handcuffs padlocked to a heavy chain at her waist, her ankles shackled together in leg irons. Pamela Colloff, ProPublica, 24 Mar. 2026 The organization added that some of the canines were tied with heavy chains anchored to the ground and plastic barrels. Moná Thomas, PEOPLE, 18 Nov. 2025 Bottom trawlers are filmed towing nets with a heavy chain along the seafloor, indiscriminately catching creatures in their path and churning up dense clouds of carbon-rich sediment. Nell Lewis, CNN Money, 8 May 2025 Police seized several dogs, treadmills, livestock vitamins, heavy chains, tires and metal poles from Washington’s residence in the 4800 block of Tallman Street in south Fort Worth, according to a list of evidence in the case. Lillie Davidson, Fort Worth Star-Telegram, 7 May 2025 See All Example Sentences for heavy chain

Word History

First Known Use

1964, in the meaning defined above

Time Traveler
The first known use of heavy chain was in 1964

Browse Nearby Words

Cite this Entry

“Heavy chain.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/heavy%20chain. Accessed 1 Apr. 2026.

Medical Definition

heavy chain

noun
: either of the two larger of the four polypeptide chains comprising antibodies compare light chain
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