goldenseal

noun

gold·​en·​seal ˈgōl-dən-ˌsēl 

: a perennial North American herb (Hydrastis canadensis) of the buttercup family with large leaves and a thick knotted yellow rhizome sometimes used medicinally

Examples of goldenseal in a Sentence

Recent Examples on the Web

Berberine, a compound found in herbs like barberry and goldenseal, has gained popularity for its potential to support weight, blood sugar, and heart health naturally. —Karen Berger, Verywell Health, 5 Nov. 2025

The developer went on to say the proprietary blend featured in this collection combines bioactive CO2 extracts, including goldenrod and goldenseal. —Dahvi Shira, Forbes.com, 22 Aug. 2025

Yenzirbo used a makeshift metal digger crafted from an old golf club to point out a four-lobed ginseng plant growing on a steep slope among a mosaic of other medicinal plants—black cohosh, goldenseal, nettle. —Greg Kahn, National Geographic, 9 Jan. 2020

My own research also revealed that goldenseal does have the potential to interact with other drugs. —Allyson Byers, SELF, 1 June 2018

Kay and her bears lived in the middle of some 5,000 acres of swampy forest, thick with muck peat and goldenseal and pine trees, in Tyrrell County, in northeastern North Carolina. —Brandon Sneed, Outside Online, 4 Apr. 2016

Word History

First Known Use

1839, in the meaning defined above

Rhymes for goldenseal

• afebrile
• bookmobile
• cochineal
• nonideal
• peroneal
• philomel
• popliteal
• snowmobile
• waterwheel
• abele
• alkyl
• anneal

Medical Definition

goldenseal

noun

gold·​en·​seal ˈgōl-dən-ˌsēl 

1

: a perennial American herb of the genus Hydrastis (H. canadensis) with large leaves and a thick knotted yellow rhizome sometimes used medicinally

2

: hydrastis sense 2