: to heat and then cool (a material, such as steel or glass) usually for softening and making less brittle
: to cool slowly usually in a furnace
- Each bar, with its intricate twists, bevels and turns, had to be shaped individually. This shaping made some parts of the bars brittle … . To restore their flexibility, all the bars had to be annealed by heating, and then rapidly cooling them.
- —Ivars Peterson
: to cause two complementary strands of nucleic acid (such as DNA or RNA) to join by hydrogen bonding
: to induce the binding of a genetic primer (see 2primer 3) to a complementary single-stranded nucleic acid by slowly cooling single strands obtained from the heating and separation of double-stranded DNA or RNA
- During repair of DNA double-strand breaks, cells must accurately anneal broken strands …
- —Seiji N. Sugiman-Marangos et al.
- The primers are annealed to the single strands when the local temperature is reduced to between 50 and 65 C.
- — Andrew J. DeMello
- During PCR, fragments are heated so they will separate into single strands. A short nucleotide sequence called a primer is then annealed to each original template.
- —George M. Church
: to pair with a complementary strand of nucleic acid
: to bind to a complementary single-stranded nucleic acid during a process of heating and cooling
- A microRNA molecule can anneal to a messenger RNA (mRNA) containing a nucleotide sequence that complements the sequence of the microRNA …
- —Carlo M. Croce
- Site-specific primers, designed to complement the base pairs of the DNA region flanking the target, anneal to these regions.
- —Norman Arnhelm and Corey H. Levenson
: strengthen, toughen
- Mildred at least, is capable of love. In Veda, love has been annealed to a hard diamond of ambition.
- —Stephen King