Medical Dictionary

glucagon–like peptide


Medical Definition of glucagon–like peptide

  1. :  either of two intestinal hormones secreted together when nutrients (such as carbohydrates and lipids) are present in the small intestine:a or glucagon–like peptide 1 :  one that stimulates insulin secretion and inhibits glucagon secretion, stomach emptying, and food intake The Food and Drug Administration (FDA) has approved agents that increase blood glucagon-like peptide 1 (GLP-1) activity or levels and stimulate insulin secretion (in a glucose-dependent manner) while inhibiting glucagon secretion.—Faramarz Ismail-Beigi, The New England Journal of Medicine, 5 Apr. 2012b or glucagon–like peptide 2 :  one that stimulates cell proliferation in the intestinal mucosa and has little effect on insulin secretion

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capable of being understood in two ways

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