Medical Dictionary

glucagon-like peptide

noun

medical Definition of glucagon-like peptide

:either of two intestinal hormones secreted together when nutrients (such as carbohydrates and lipids) are present in the small intestine:
a or glucagon-like peptide 1 :one that stimulates insulin secretion and inhibits glucagon secretion, stomach emptying, and food intake
  • The Food and Drug Administration (FDA) has approved agents that increase blood glucagon-like peptide 1 (GLP-1) activity or levels and stimulate insulin secretion (in a glucose-dependent manner) while inhibiting glucagon secretion.
  • —Faramarz Ismail-BeigiThe New England Journal of Medicine5 Apr. 2012
b or glucagon-like peptide 2 :one that stimulates cell proliferation in the intestinal mucosa and has little effect on insulin secretion

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