gastrointestinal

adjective

gas·​tro·​in·​tes·​ti·​nal ˌga-strō-in-ˈte-stə-nᵊl How to pronounce gastrointestinal (audio)
-ˈtes(t)-nəl
: of, relating to, affecting, or including both stomach and intestine

Examples of gastrointestinal in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Deficiency may also come about from gastrointestinal blood loss, which can be an early sign of colon cancer. — Amanda Schupak, CNN Money, 23 Oct. 2026 Shigellosis is a gastrointestinal illness caused by a group of bacteria called Shigella. — Devika Rao, TheWeek, 23 Oct. 2026 For those with a sesame allergy, consuming products containing the seed can lead to anaphylaxis and cause breathing issues, cardiovascular distress, hives, and gastrointestinal problems. — Anne Ewbank, Sacbee.com, 23 Oct. 2026 Some people notice differences in appetite, cravings, or gastrointestinal (GI) tolerance depending on the sweetener used. — Brittany Poulson, Verywell Health, 23 Oct. 2026 See All Example Sentences for gastrointestinal

Word History

First Known Use

1831, in the meaning defined above

Time Traveler
The first known use of gastrointestinal was in 1831

Cite this Entry

“Gastrointestinal.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/gastrointestinal. Accessed 27 Oct. 2026.

Kids Definition

gastrointestinal

adjective
: of, relating to, or including both stomach and intestine

Medical Definition

gastrointestinal

adjective
: of, relating to, or affecting both stomach and intestine
gastrointestinal distress
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