frontotemporal dementia

variants: also frontotemporal degeneration

Medical Definition of frontotemporal dementia

: any of several degenerative brain diseases that are caused by progressive atrophic changes in the frontal or temporal lobes, that usually start in late middle age, that result in changes to behavior and personality (such as impulsiveness, social impropriety, and apathy) and typically impaired language function, and that lead in advanced cases to a profound decline in cognitive and language functioning Alzheimer disease is the most common cause of dementia, but similar impairment of intellectual functioning occurs with many other brain disorders, such as frontotemporal dementia (FTD). After AD, FTD is the second most prevalent cause of early-onset dementia (occurring before age 65 years).— M. J. Friedrich, Journal of the American Medical Association, 11 July 2007

Note: Pick's disease and sometimes progressive supranuclear palsy are classified as frontotemporal dementias.

abbreviation FTD

Learn More about frontotemporal dementia

Share frontotemporal dementia

Resources for frontotemporal dementia

Comments on frontotemporal dementia

What made you want to look up frontotemporal dementia? Please tell us where you read or heard it (including the quote, if possible).


a flaw that causes the downfall of a hero

Get Word of the Day daily email!

Test Your Vocabulary

A Green Quiz

  • shamrock
  • What is the best definition of green-eyed monster?
Name That Thing

Test your visual vocabulary with our 10-question challenge!

Dictionary Devil

Test Your Knowledge - and learn some interesting things along the way.


Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!