: relating to, being, or causing physiological changes in the body (such as an increase in heart rate or dilation of bronchi) in response to stress
epinephrine is a fight-or-flight hormone
a fight-or-flight reaction

Examples of fight-or-flight in a Sentence

Recent Examples on the Web
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As the gut is considered a second brain, the process involves listening in with a stethoscope while manual, hands-on therapy helps the body shift more easily between fight-or-flight and not get stuck in one. Lydia Bell, Condé Nast Traveler, 23 June 2026 The concept is rooted in the autonomic nervous system, which includes the sympathetic nervous system—responsible for the body's fight-or-flight response—and the parasympathetic nervous system, which helps promote rest, recovery and restoration. Meggen Harris, Forbes.com, 21 June 2026 Oxytocin shifts your body out of fight-or-flight mode. Laura Kiniry, Popular Science, 17 June 2026 The defense will argue Gormley went for the Taser, exposing its pistol grip and triggering a fight-or-flight response in Harrison, who believed his life was in danger, Winter told jurors. Nate Gartrell, Mercury News, 16 June 2026 See All Example Sentences for fight-or-flight

Word History

First Known Use

1973, in the meaning defined above

Time Traveler
The first known use of fight-or-flight was in 1973

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Cite this Entry

“Fight-or-flight.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/fight-or-flight. Accessed 30 Jun. 2026.

Medical Definition

fight-or-flight

adjective
ˌfī-tər-ˈflīt
: relating to, being, or causing physiological changes in the body (such as an increase in heart rate or dilation of bronchi) in response to stress
the fight-or-flight response
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