: an antibiotic with broad antineoplastic activity that is obtained from a bacterium (Streptomyces peucetius) and is administered in the form of its hydrochloride C27H29NO11·HCl

Examples of doxorubicin in a Sentence

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The greatest risk is from the chemotherapy drug doxorubicin, an anthracyclin. NBC News, 2 Feb. 2018 The chemotherapy drug, doxorubicin, damaged Shae's heart, but her cancer required the most aggressive treatment possible to stop the tumors from spreading. David Haugh, chicagotribune.com, 29 Sep. 2017 The ability to localize doxorubicin at the tumor could reduce its dangerous cardiovascular side effects. Sarah Anderson, Discover Magazine, 21 Mar. 2022 Treatment included four rounds of doxorubicin, four rounds of paclitaxel, and 21 radiation treatments. Ayren Jackson-Cannady, SELF, 29 May 2026 Despite the concerns, another FDA group — tasked with preventing drug shortages — reached out to Sun after the inspection to make sure that the factory would continue to produce the cancer drug doxorubicin. Megan Rose, ProPublica, 12 Aug. 2025

Word History

Etymology

deoxy- + -orubicin (as in daunorubicin)

First Known Use

1971, in the meaning defined above

Time Traveler
The first known use of doxorubicin was in 1971

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Cite this Entry

“Doxorubicin.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/doxorubicin. Accessed 7 Jul. 2026.

Medical Definition

doxorubicin

noun
: an anthracycline antibiotic with broad antineoplastic activity that is obtained from a bacterium of the genus Streptomyces (S. peucetius) and is administered in the form of its hydrochloride C27H29NO11·HCl

Note: Doxorubicin is marketed under the trademark Adriamycin and is used in combination with other drugs in the treatment of Hodgkin's lymphoma (see abvd).

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