Medical Definition of dihydrofolate reductase
Note: Dihydrofolate reductase plays an important role in DNA synthesis and is targeted by some anticancer and antimicrobial drugs (such as methotrexate and trimethoprim) in order to inhibit its positive effect on cell growth and reproduction.… an enzyme called dihydrofolate reductase or DHFR, a catalyst that is essential to nucleic acid synthesis and cell growth.— Warren Froelich, The San Diego Union-Tribune, 20 Oct. 1985 —abbreviation DHFR
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