depletion

noun
de·​ple·​tion | \ di-ˈplē-shən How to pronounce depletion (audio) \

Medical Definition of depletion

: the act or process of depleting or the state of being depleted: as
a : the reduction or loss of blood, body fluids, chemical constituents, or stored materials from the body (as by hemorrhage or malnutrition)
b : a debilitated state caused by excessive loss of body fluids or other constituents

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