depletion

noun
de·​ple·​tion | \di-ˈplē-shən \

Medical Definition of depletion 

: the act or process of depleting or the state of being depleted: as

a : the reduction or loss of blood, body fluids, chemical constituents, or stored materials from the body (as by hemorrhage or malnutrition)

b : a debilitated state caused by excessive loss of body fluids or other constituents

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