Medical Dictionary

depolarization

noun de·po·lar·iza·tion
variants: or British depolarisation play \(ˌ)dē-ˌpō-lə-rə-ˈzā-shən\

medical Definition of depolarization

: loss of polarization; especially : loss of the difference in charge between the inside and outside of the plasma membrane of a muscle or nerve cell due to a change in permeability and migration of sodium ions to the interior
  • … partial depolarization of the ventricular tissue resulting from rapid conduction of the electrical impulse from the atrium to the ventricle …
  • —Mark S. LinkThe New England Journal of Medicine11 Oct. 2012

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