Medical Definition of chimeric
1: relating to, derived from, or being a genetic chimera : containing tissue with two or more genetically distinct populations of cells chimeric mice
2: composed of material (such as DNA or polypeptide) from more than one organism a chimeric gene … scientists have created so-called chimeric antibodies, using genetic engineering to fuse variable regions derived from mouse antibodies with a constant region derived from human antibodies.—Lawrence M. Fisher, The New York Times, 5 Mar. 1991
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