ceramide
noun
cer·amide
ˈsir-ə-ˌmīd 
ˈser-
plural ceramides
: any of various simple sphingolipids that are composed of a fatty acid linked to sphingosine, are found especially in cell membranes, are involved in mediating various cellular processes (such as those affecting cell differentiation and apoptosis), and act as precursors for more complex sphingolipids
The enzyme controls production of a cellular substance, ceramide, which triggers the natural process of egg cell death.—
L. Stivitz
L. StivitzMoisturizers containing ceramides (natural lipids that are similar in structure to those in the skin's own moisture barrier) … are also worthwhile splurges for women with dry or problem skin, according to independent tester Grove.—Constance Cardozo
Constance CardozoExamples of ceramide in a Sentence
Recent Examples on the Web
The overnight mask uses four key ingredients to help produce a glowy complexion, including ceramide NP for hydration, collagen extract to assist with skin elasticity, adenosine to minimize fine lines, and niacinamide, which helps even skin tone.
—Rylee Johnston, People.com, 3 Aug. 2025
Heard recommends starting with a gentle cleanser, followed by an essence or serum with hydrating and reparative ingredients, and finishing with a moisturizer rich in ceramides and fatty acids.
—Essence, 31 July 2025
In addition to barrier-repairing ceramides, the formula includes salicylic acid to clear pores and gently exfoliate, as well as hyaluronic acid and niacinamide to deeply hydrate, soothe, and strengthen the skin.
—Christa Joanna Lee, Allure, 20 July 2025
There’s also hyaluronic acid to draw in moisture and plump fine lines, plus ceramides help strengthen the skin’s moisture barrier.
—Celia Shatzman, Forbes.com, 8 July 2025
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Rylee Johnston, People.com, 3 Aug. 2025
Heard recommends starting with a gentle cleanser, followed by an essence or serum with hydrating and reparative ingredients, and finishing with a moisturizer rich in ceramides and fatty acids.
—Essence, 31 July 2025
In addition to barrier-repairing ceramides, the formula includes salicylic acid to clear pores and gently exfoliate, as well as hyaluronic acid and niacinamide to deeply hydrate, soothe, and strengthen the skin.
—Christa Joanna Lee, Allure, 20 July 2025
There’s also hyaluronic acid to draw in moisture and plump fine lines, plus ceramides help strengthen the skin’s moisture barrier.
—Celia Shatzman, Forbes.com, 8 July 2025
See All Example Sentences for ceramide
Cite this Entry
“Ceramide.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/ceramide. Accessed 22 Aug. 2025.
Copy CitationMedical Definition
ceramide
noun
cer·amide
ˈsir-ə-ˌmīd
: any of a group of amido sphingolipids formed by linking a fatty acid to sphingosine and found widely in small amounts in plant and animal tissue
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