ceramide

noun

cer·​amide ˈsir-ə-ˌmīd How to pronounce ceramide (audio)
ˈser-
plural ceramides
: any of various simple sphingolipids that are composed of a fatty acid linked to sphingosine, are found especially in cell membranes, are involved in mediating various cellular processes (such as those affecting cell differentiation and apoptosis), and act as precursors for more complex sphingolipids
The enzyme controls production of a cellular substance, ceramide, which triggers the natural process of egg cell death.L. Stivitz
Moisturizers containing ceramides (natural lipids that are similar in structure to those in the skin's own moisture barrier) … are also worthwhile splurges for women with dry or problem skin, according to independent tester Grove.Constance Cardozo

Examples of ceramide in a Sentence

Recent Examples on the Web
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In addition to providing a temporary glow, the formula features skin-benefiting ingredients such as ceramides, vitamin E, and glycerin for long-term benefits, too. Gina Vaynshteyn, StyleCaster, 30 June 2026 Barrier-supporting ingredients like ceramides may also help keep skin comfortable, while antioxidants like vitamin E or green tea extract can offer additional protection against environmental stressors. Brigitt Earley, Glamour, 25 June 2026 The specially emulsified formula keeps the ceramides evenly dispersed (no shaking required), while the lightweight mist feels especially refreshing on hot, humid summer days. Christa Joanna Lee, Allure, 24 June 2026 It's formulated with barrier-strengthening ceramides, moisturizing shea butter, gently exfoliating urea, and lactic acid. Essence Wiley, InStyle, 24 June 2026 See All Example Sentences for ceramide

Word History

Etymology

cerebroside + amide

First Known Use

1958, in the meaning defined above

Time Traveler
The first known use of ceramide was in 1958

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Cite this Entry

“Ceramide.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/ceramide. Accessed 4 Jul. 2026.

Medical Definition

ceramide

noun
cer·​amide ˈsir-ə-ˌmīd How to pronounce ceramide (audio)
: any of a group of amido sphingolipids formed by linking a fatty acid to sphingosine and found widely in small amounts in plant and animal tissue

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