bortezomib

noun
bor·​tez·​o·​mib | \ ˌbȯr-ˈte-zō-ˌmib How to pronounce bortezomib (audio) \

Medical Definition of bortezomib

: an antineoplastic drug C19H25BN4O4 administered by intravenous or subcutaneous injection especially in the treatment of multiple myeloma

Note: Bortezomib inhibits the activity of proteolytic proteasomes, which results in an increased concentration of proteins in a cell. This buildup of proteins is thought to induce apoptosis in some types of cancer cells. Bortezomib is marketed under the trademark Velcade.

Bortezomib induces apoptosis in a wide variety of cancer-cell lines and other transformed cells, yet it has relatively few toxic effects on normal cells.— Beverly S. Mitchell, The New England Journal of Medicine, 26 June 2003

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Dictionary Entries Near bortezomib

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Cite this Entry

“Bortezomib.” Merriam-Webster.com Medical Dictionary, Merriam-Webster, https://www.merriam-webster.com/medical/bortezomib. Accessed 22 Jan. 2022.

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