Medical Dictionary

biallelic

adjective bi·al·le·lic \ (ˈ)bī-ə-ˈlē-lik, -ˈle- \

medical Definition of biallelic

:of, relating to, or affecting both alleles of a gene
  • The risk of colorectal cancer among carriers of biallelic mutations appears to be close to 100% by 60 years of age …
  • —William D. FoulkesThe New England Journal of Medicine13 Nov. 2008
  • This mode of oncogenesis differs from the inactivation of most tumor-suppressor genes, which are biallelic—that is, one allele is inactivated in the germ line, followed by mutation of the second allele at the somatic-cell level.
  • —Roel NusseScience18 May 2007

Seen and Heard

What made you want to look up biallelic? Please tell us where you read or heard it (including the quote, if possible).

Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!

WORD OF THE DAY

to suppress quietly or indirectly

Get Word of the Day daily email!

Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!