biallelic

adjective
bi·​al·​le·​lic | \ (ˈ)bī-ə-ˈlē-lik, -ˈle- How to pronounce biallelic (audio) \

Medical Definition of biallelic

: of, relating to, or affecting both alleles of a gene The risk of colorectal cancer among carriers of biallelic mutations appears to be close to 100% by 60 years of age …— William D. Foulkes, The New England Journal of Medicine, 13 Nov. 2008 This mode of oncogenesis differs from the inactivation of most tumor-suppressor genes, which are biallelic—that is, one allele is inactivated in the germ line, followed by mutation of the second allele at the somatic-cell level.— Roel Nusse, Science, 18 May 2007

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Cite this Entry

“Biallelic.” Merriam-Webster.com Medical Dictionary, Merriam-Webster, https://www.merriam-webster.com/medical/biallelic. Accessed 29 Sep. 2020.

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