SINCE 1828
bacterial artificial chromosome
nounMedical Definition of bacterial artificial chromosome
: a genetically engineered bacterial chromosome that is used as a vector to clone DNA segments, that is introduced for cloning into a bacterium (E. coli) where it is maintained as a plasmid, and into which a segment of foreign DNA up to about 300 kilobases in length may be spliced for cloning
—abbreviation BAC
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