Medical Dictionary

autoreactive

adjective au·to·re·ac·tive \ ˌȯt-ō-rē-ˈak-tiv \

medical Definition of autoreactive

: produced by an organism and acting against its own cells or tissues
  • It has been presumed that autoreactive B cells, like normal B cells, accumulate in the follicles of lymphoid tissues after encountering antigen and begin to proliferate, producing high-affinity autoantibodies and forming germinal centers.
  • —Yang-Xin Fu and Ursula StorbScience20 Sept. 2002

autoreactivity

play \ˌȯt-ō-(ˌ)rē-ˌak-ˈti-və-tē\ noun plural autoreactivities
    • At the same time, autoreactivity of B cells and T cells is present in all normal persons, and a complex set of regulatory mechanisms is required to prevent overt destruction of tissue through autoimmunity.
    • —Peter K. GregersenThe New England Journal of Medicine22 Mar. 2007

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