Medical Dictionary

atrophic gastritis


Medical Definition of atrophic gastritis

  1. :  chronic inflammation of the mucous membrane of the stomach leading to atrophy and thinning of parts of the gastric mucosa and often gastric metaplasia Atrophic gastritis may result from a chronic infection with the bacterium Helicobacter pylori or from an autoimmune response destructive to glandular cells of the stomach. <Atrophic gastritis can lead to the loss of certain important gastric cells and the replacement of them with intestinal-type tissue, a direct precursor to gastric cancer.—Dustin Garth James and Liz Scott, The Complete Idiot's Guide to Digestive Health, 2010> <H. pylori has been linked to chronic atrophic gastritis, an established precursor of the intestinal type of gastric carcinoma.—Julie Parsonnet, The New England Journal of Medicine, 17 Oct. 1991>

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