antibody

noun

an·​ti·​body ˈan-ti-ˌbä-dē How to pronounce antibody (audio)
: any of a large number of proteins of high molecular weight that are produced normally by specialized B cells after stimulation by an antigen and act specifically against the antigen in an immune response, that are produced abnormally by some cancer cells, and that typically consist of four subunits including two heavy chains and two light chains

called also immunoglobulin

Examples of antibody in a Sentence

Recent Examples on the Web
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That triggers the development of antibodies — immune system proteins that fight off foreign invaders — that quickly learn to identify and attack alpha-gal sugar molecules. Matthew Perrone, Fortune, 13 June 2026 The antibody acts like a delivery address. William A. Haseltine, Forbes.com, 11 June 2026 Lederman said the injection of Borrelia antibodies has been in the works at the University of Massachusetts for the last ten years. Allison Gollenberg, Hartford Courant, 9 June 2026 In the absence of active lesions to swab for HSV itself, tests must evaluate the immune response to the virus in a patient’s blood, typically by screening for the immunoglobulin G (IgG) antibody. Lauren Schneider, Scientific American, 9 June 2026 See All Example Sentences for antibody

Word History

First Known Use

1894, in the meaning defined above

Time Traveler
The first known use of antibody was in 1894

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Cite this Entry

“Antibody.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/antibody. Accessed 16 Jun. 2026.

Kids Definition

antibody

noun
an·​ti·​body ˈant-i-ˌbäd-ē How to pronounce antibody (audio)
: a substance produced by special cells of the body that combines with an antigen and counteracts its effects or those of the microscopic plant or animal on which the antigen may occur

Medical Definition

antibody

noun
an·​ti·​body ˈant-i-ˌbäd-ē How to pronounce antibody (audio)
plural antibodies
: any of a large number of proteins of high molecular weight that are produced normally by specialized B cells after stimulation by an antigen and act specifically against the antigen in an immune response, that are produced abnormally by some cancer cells, and that typically consist of four subunits including two heavy chains and two light chains

called also immunoglobulin

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