Medical Dictionary

ankyrin

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noun an·ky·rin \ ˈaŋ-kə-rən \

medical Definition of ankyrin

:any of a family of proteins that link spectrin in the cytoskeleton to proteins in the cell membrane and play a role in maintaining membrane stability
  • Ankyrins were originally identified in erythrocytes and, in addition to the heart, they are also expressed in brain, kidney, skeletal muscle, liver and lung.
  • —Sabina Kuperschmidt et al., in Cardiovascular Genetics and Genomics for the Cardiologist2007
often followed by a number or a letter to indicate type
  • The defect is a mutation of a gene that codes for a protein called ankyrin-B, which plays an important but until now unknown role in the complex series of electrical and chemical events that govern the heartbeat.
  • The Chicago Tribune9 Feb. 2003

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