spectrin

noun

spec·​trin ˈspek-trən How to pronounce spectrin (audio)
: a large cytoskeletal protein that is found on the inner cell membrane of red blood cells and that functions especially in maintaining cell shape
The erythrocyte cytoskeleton, which consists primarily of a meshwork of spectrin and actin, controls cell shape and the disposition of protein within the membrane.Robert Siman et al., Nature
A number of genetic diseases (hemolytic anemias) characterized by fragile, abnormally shaped erythrocytes have been traced to mutations in ankyrin or spectrin.Gerald Karp, Cell and Molecular Biology: Concepts and Experiments, 6th edition

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Cite this Entry

“Spectrin.” Merriam-Webster.com Medical Dictionary, Merriam-Webster, https://www.merriam-webster.com/medical/spectrin. Accessed 7 Feb. 2023.

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