acetylcholine

noun

ace·​tyl·​cho·​line ə-ˌse-tᵊl-ˈkō-ˌlēn 

-ˌsē-;

ˈa-sə-ˌtēl-

: a neurotransmitter [C₇H₁₆NO₂]⁺ released at autonomic synapses and neuromuscular junctions and formed enzymatically in the tissues from choline

Examples of acetylcholine in a Sentence

Recent Examples on the Web

Scientists believe the treatment works by engaging neuromodulatory systems in the brain, particularly pathways involving norepinephrine and acetylcholine. —Samantha Agate, Fort Worth Star-Telegram, 8 June 2026

Specifically, many α-neurotoxins from the venom latch onto the receptor before the acetylcholine can reach it. —Scott Travers, Forbes.com, 31 May 2026

Choline helps produce acetylcholine, a neurotransmitter that plays a role in memory, mood, and cognition. —Abby Norman, Verywell Health, 6 Apr. 2026

Pert described how neurotransmitters such as dopamine, norepinephrine, and acetylcholine act as a mail system throughout a body and govern its actions. —Sally Jenkins, The Atlantic, 21 Feb. 2026

Word History

Etymology

borrowed from German Acetylcholin, from Acetyl acetyl + Cholin choline

First Known Use

1906, in the meaning defined above

Rhymes for acetylcholine

• succinylcholine
• phosphatidylcholine

Kids Definition

acetylcholine

noun

ace·​tyl·​cho·​line ə-ˌset-ᵊl-ˈkō-ˌlēn 

-ˌsēt-;

ˈas-ə-ˌtēl-

: a compound released at autonomic nerve endings that functions in carrying nerve impulses

Medical Definition

acetylcholine

noun

ace·​tyl·​cho·​line ə-ˌset-ᵊl-ˈkō-ˌlēn  -ˌsēt-; ˌas-ə-ˌtēl- 

: a neurotransmitter [C₇H₁₆NO₂]⁺ released at autonomic synapses and neuromuscular junctions, active in the transmission of nerve impulses, and formed enzymatically in the tissues from choline

acetylcholinic

-kō-ˈlin-ik 

adjective