Sim·monds' disease | \ ˈsim-ən(d)z- 
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\Medical Definition of Simmonds' disease
: a disease characterized by panhypopituitarism that causes progressive emaciation, atrophy of the gonads, thyroid, and adrenal cortex, and loss of body hair and that results from atrophy or destruction of the anterior lobe of the pituitary gland
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