Medical Definition of MDR

1 minimum daily requirement
2 multidrug-resistant; multidrug resistance Second-line drugs … are essential for treating multidrug-resistant and extensively drug-resistant tuberculosis (MDR TB and XDR TB).— Barbara J. Seaworth et al., The Journal of the American Medical Association, 6 Mar. 2013 … a community-acquired strain of MRSA that causes community-acquired pneumonia in previously healthy patients without health care–associated pneumonia or other risk factors for MDR pathogens has increasingly been recognized.— Richard G. Wunderink and Grant W. Waterer, The New England Journal of Medicine, 6 Feb. 2014

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something desired as essential

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