Medical Dictionary

Charcot-Marie-Tooth disease

noun Char·cot-Ma·rie-Tooth disease \ (ˌ)shär-ˌkō-mə-ˌrē-ˈtüth- \
variants: also Charcot-Marie-Tooth

medical Definition of Charcot-Marie-Tooth disease

:an inherited neurological disorder affecting the peripheral nerves that is marked especially by progressive muscular weakness in the foot and lower leg and later the forearms and hands and that typically has an onset during adolescence or early adulthood called also peroneal muscular atrophy

Biographical Note for charcot-marie-tooth disease

  • Tooth, Howard Henry (1856–1925), British physician. Tooth enjoyed a varied career as a consulting physician to a British hospital for paralyzed and epileptic patients, as an examiner in medicine at Cambridge and Durham universities, and as physician to British troops in Malta. In 1886 he published a description of a disease marked by progressive muscular atrophy. In that same year an independent description of the disease was published jointly by Jean-Martin Charcot and Pierre Marie.

  • Seen and Heard

    What made you want to look up Charcot-Marie-Tooth disease? Please tell us where you read or heard it (including the quote, if possible).

    Love words? Need even more definitions?

    Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!

    WORD OF THE DAY

    to suppress quietly or indirectly

    Get Word of the Day daily email!

    Love words? Need even more definitions?

    Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!