Medical Dictionary

Arnold-Chiari malformation

noun Ar·nold-Chi·ari malformation \ ˈär-nᵊld-kē-ˈär-ē- \

medical Definition of Arnold-Chiari malformation

: a congenital abnormality in which the lower surface of the cerebellum and the lower brain stem protrude into the spinal canal through the foramen magnum
  • She was born with Arnold-Chiari malformation, a rare and random birth defect that occurs, according to one study, in about 8 of 100,000 people. A deformity of the base of the skull and spine, it can cause chronic pain and loss of balance.
  • —Arthur AllenThe Washington Post23 Feb. 1997
Note: Arnold-Chiari malformation often occurs with spina bifida and hydrocephalus. It is classified as a type of Chiari malformation.

Biographical Note for arnold-chiari malformation

  • Chiari, Hans (1851–1916), Austrian pathologist. Chiari served as a professor of pathological anatomy first at the University of Prague and from 1906 at the University of Strasbourg. Most of his research and writings, of which there are more than 177, were the result of his postmortem examinations. In the 1890s he described a condition in children involving deformities of the cerebellum and brainstem, with herniation of the spinal cord. The condition is sometimes associated with his name alone and sometimes jointly with the name of Julius Arnold.

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