X chromosome

noun

: a sex chromosome that usually occurs paired in each female cell and single in each male cell in species in which the male typically has two unlike sex chromosomes compare y chromosome

Examples of X chromosome in a Sentence

Recent Examples on the Web
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Located on the X chromosome, ZFX belongs to a small group of genes that escape a process known as X chromosome inactivation. — Daniella Gray, MSNBC Newsweek, 6 Nov. 2026 In most cases, genes on one of the two X chromosomes in each cell are naturally switched off, preventing excessive doses of their products. — New Atlas, 5 Nov. 2026 This process turned the embryos female with just a single X chromosome—typically notated as XO. — Gennaro Tomma, Scientific American, 13 Oct. 2026 Most females inherit two X chromosomes (XX), whereas most males inherit one X and one Y chromosome (XY). — Encyclopedia Britannica, 13 July 2026 See All Example Sentences for X chromosome

Word History

First Known Use

1911, in the meaning defined above

Time Traveler
The first known use of X chromosome was in 1911

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Cite this Entry

“X chromosome.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/X%20chromosome. Accessed 14 Nov. 2026.

Kids Definition

X chromosome

noun
: a sex chromosome that is associated with femaleness and usually occurs paired in each female cell and single in each male cell in organisms (as human beings) in which the male normally has two unlike sex chromosomes compare y chromosome

Medical Definition

X chromosome

noun
: a sex chromosome that usually occurs paired in each female cell and single in each male cell in species in which the male typically has two unlike sex chromosomes compare y chromosome

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