vasoconstrictive

adjective
va·so·con·stric·tive | \ˌvā-zō-kən-ˈstrik-tiv \

Definition of vasoconstrictive 

: inducing vasoconstriction

First Known Use of vasoconstrictive

1890, in the meaning defined above

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The first known use of vasoconstrictive was in 1890

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vasoconstrictive

adjective
va·so·con·stric·tive | \-ˈstrik-tiv \

Medical Definition of vasoconstrictive 

: inducing vasoconstriction a vasoconstrictive agent

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