: any of a class of drugs (such as sumatriptan) that bind to and are agonists of serotonin receptors and are used to treat migraine attacks

Examples of triptan in a Sentence

Recent Examples on the Web
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Ideally such pain relievers would be in pill form and would not constrict blood vessels, as triptans do. R. Allan Purdy, Scientific American, 1 May 2017 In addition, medications known as triptans are used to treat migraines. Maggie O'Neill, Health.com, 11 July 2019 Due to this mechanism, health experts say triptans might not be safe for people with cardiovascular disease or high blood pressure. Adrianna Rodriguez, USA TODAY, 10 Mar. 2023 This mode of action, however, means triptans are not considered safe for use by people at risk of cardiovascular disease and stroke. Meera Senthilingam, CNN, 19 Nov. 2019 Currently, the other non-pill rapid migraine relief medications on the market are in injection form and a nasal spray, but those are a class of medication known as triptans. Mallory Rowley, ABC News, 10 Mar. 2023

Word History

Etymology

-triptan (as in sumatriptan)

First Known Use

1997, in the meaning defined above

Time Traveler
The first known use of triptan was in 1997

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Cite this Entry

“Triptan.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/triptan. Accessed 7 Jul. 2026.

Medical Definition

: any of a class of drugs (as sumatriptan) that bind to and are agonists of serotonin receptors, that are used to treat migraine attacks, and that are thought to function by producing vasoconstriction of cranial blood vessels, by inhibiting secretion of inflammatory neuropeptides, and by blocking neurotransmission of pain
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