testosterone

noun

tes·​tos·​ter·​one te-ˈstä-stə-ˌrōn 

1

: a hormone that is a hydroxy steroid ketone C₁₉H₂₈O₂ produced especially by the testes or made synthetically and that is responsible for inducing and maintaining male secondary sex characters

2

: qualities (such as brawn and aggressiveness) usually associated with males : manliness

Examples of testosterone in a Sentence

Recent Examples on the Web

This was reportedly linked to naturally high testosterone levels that CAF claimed were higher than the federation’s limit. —Tamerra Griffin, New York Times, 11 July 2025

Relatively more testosterone floating around in your system can cause your hair follicles to shrink over time, Dr. Engelman says. —Erica Sloan, SELF, 9 July 2025

Up to a third of men receiving testosterone therapy don’t meet the official clinical criteria for testosterone deficiency. —Dr. Jamin Brahmbhatt, CNN Money, 8 July 2025

They are also known to be endocrine disruptors, chemicals that interfere with our endocrine systems, which control the body’s hormones—such as insulin, testosterone, and estrogen—and numerous bodily functions, including metabolism and blood sugar regulation. —Ani Freedman, Fortune, 26 June 2025

Word History

Etymology

borrowed from German Testosteron, from Latin testēs testes + German -o- -o- + -steron -sterone

Note: The name was introduced by the Hungarian pharmacologists Karoly Gyula David (1905-45) and János Freud (1901-48), the Dutch endocrinologist Elisabeth Dingemanse (1886-1952), and the German-born Dutch physician and pharmacologist Ernst Laqueur (1880-1947) (all affiliated with the Pharmaco-Therapeutic Laboratory of the University of Amsterdam) in "Über krystallinisches männliches Hormon aus Hoden (Testosteron), wirksamer als aus Harn oder aus Cholesterin bereitetes Androsteron," Zeitschrift für physiologische Chemie, Band 233 (1935), pp. 281-83.

First Known Use

1935, in the meaning defined at sense 1

Rhymes for testosterone

• aldosterone
• anticyclone
• progesterone
• acetone
• anglophone
• baritone
• bourguignon
• buspirone
• chaperon
• chaperone
• cobblestone
• collarbone

Kids Definition

testosterone

noun

tes·​tos·​ter·​one te-ˈstäs-tə-ˌrōn 

: a male hormone produced by the testes that causes the development of the male reproductive system and secondary sex characteristics

Medical Definition

testosterone

noun

tes·​tos·​ter·​one te-ˈstäs-tə-ˌrōn 

: a male hormone that is a crystalline hydroxy steroid ketone C₁₉H₂₈O₂ produced primarily by the testes or made synthetically and that is the main androgen responsible for inducing and maintaining male secondary sex characteristics see androgel, axiron