telomerase

noun

tel·​o·​me·​rase te-ˈlō-mə-ˌrās How to pronounce telomerase (audio)
-ˌrāz
: a DNA polymerase that is a ribonucleoprotein catalyzing the elongation of chromosomal telomeres in eukaryotic cell division and is particularly active in cancer cells

Example Sentences

Recent Examples on the Web Our discoveries of telomeres and telomerase open a Pandora’s box of difficult questions. Veronique Greenwood, Discover Magazine, 18 May 2011 In the 1990s, scientists at the Bay Area biotech company Geron Corporation mapped the human gene for telomerase. Megan Molteni, STAT, 3 May 2021 There were even indications that telomerase activity could predict treatment response. Simon Makin, Scientific American, 1 Apr. 2020 The two scientists wanted to explore the idea that differences in telomerase length in T cells could explain the large disparity in the average age of onset of a type of leukemia between Chinese and U.S. patients. Jeffrey Mervis, Science | AAAS, 11 Mar. 2020 During some of the heated sessions, medical doctors and anti-aging researchers argued loudly across the conference room about biomarkers, enzymes, telomerase endings of genes, and how far mitochondria might be manipulated. Zoltan Istvan, Quartz, 29 July 2019 And the bat maintains its chromosome ends through a pathway that doesn't seem to involve telomerase, the enzyme most frequently associated with that activity. John Timmer, Ars Technica, 11 June 2019 Researchers from UC Berkeley have discovered the 3D structure of the enzyme telomerase, which could lead to new advances in aging research, as well as possible new insights into cancer. Avery Thompson, Popular Mechanics, 27 Apr. 2018 Cells that are exposed to cortisol have shorter telomeres and less telomerase, which is the enzyme responsible for maintaining the ends of telomeres. Smithsonian, 22 Jan. 2018 See More

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'telomerase.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

Word History

First Known Use

1988, in the meaning defined above

Time Traveler
The first known use of telomerase was in 1988

Dictionary Entries Near telomerase

Cite this Entry

“Telomerase.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/telomerase. Accessed 4 Feb. 2023.

Medical Definition

telomerase

noun
tel·​o·​me·​rase te-ˈlō-mə-ˌrās, -ˌrāz How to pronounce telomerase (audio)
: a DNA polymerase that is a ribonucleoprotein catalyzing the elongation of chromosomal telomeres in eukaryotic cell division and is particularly active in cancer cells

More from Merriam-Webster on telomerase

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