tel·​o·​me·​rase | \ te-ˈlō-mə-ˌrās How to pronounce telomerase (audio) , -ˌrāz \

Definition of telomerase

: a DNA polymerase that is a ribonucleoprotein catalyzing the elongation of chromosomal telomeres in eukaryotic cell division and is particularly active in cancer cells

Examples of telomerase in a Sentence

Recent Examples on the Web There were even indications that telomerase activity could predict treatment response. Simon Makin, Scientific American, "Effective Psychological Therapy May Slow Cellular Aging," 1 Apr. 2020 The two scientists wanted to explore the idea that differences in telomerase length in T cells could explain the large disparity in the average age of onset of a type of leukemia between Chinese and U.S. patients. Jeffrey Mervis, Science | AAAS, "Fired cancer scientist says ‘good people are being crushed’ by overzealous probes into possible Chinese ties," 11 Mar. 2020 During some of the heated sessions, medical doctors and anti-aging researchers argued loudly across the conference room about biomarkers, enzymes, telomerase endings of genes, and how far mitochondria might be manipulated. Zoltan Istvan, Quartz, "Rich people shouldn’t be the only ones who get to live forever," 29 July 2019 And the bat maintains its chromosome ends through a pathway that doesn't seem to involve telomerase, the enzyme most frequently associated with that activity. John Timmer, Ars Technica, "Why do bats have such bizarrely long lifespans?," 11 June 2019 Researchers from UC Berkeley have discovered the 3D structure of the enzyme telomerase, which could lead to new advances in aging research, as well as possible new insights into cancer. Avery Thompson, Popular Mechanics, "Scientists Get Their First Look at the Enzyme That Could Help Battle Aging," 27 Apr. 2018 Cells that are exposed to cortisol have shorter telomeres and less telomerase, which is the enzyme responsible for maintaining the ends of telomeres. Smithsonian, "How a Mother’s Depression Shows Up in Her Baby’s DNA," 22 Jan. 2018 Available without a prescription, TA-65 is derived from astragalus root extract, a powerful antioxidant, and is said to work by activating the enzyme telomerase, which counteracts telomere shortening. Emily Dudding, Harper's BAZAAR, "How to Age Backward," 31 Mar. 2015 In an ironic twist, the current president is a woman: Nobel laureate Elizabeth Blackburn, who discovered the molecular nature of telomeres and who co-discovered telomerase, was hired in November 2015 and began work in January 2016. Meredith Wadman, Science | AAAS, "Two female scientists sue Salk Institute, alleging discrimination at 'old boys club'," 14 July 2017

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'telomerase.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of telomerase

1988, in the meaning defined above

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The first known use of telomerase was in 1988

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Cite this Entry

“Telomerase.” Dictionary, Merriam-Webster, Accessed 10 Aug. 2020.

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More Definitions for telomerase


tel·​o·​me·​rase | \ te-ˈlō-mə-ˌrās, -ˌrāz How to pronounce telomerase (audio) \

Medical Definition of telomerase

: a DNA polymerase that is a ribonucleoprotein catalyzing the elongation of chromosomal telomeres in eukaryotic cell division and is particularly active in cancer cells

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