telomerase

noun

tel·​o·​me·​rase te-ˈlō-mə-ˌrās How to pronounce telomerase (audio)
-ˌrāz
: a DNA polymerase that is a ribonucleoprotein catalyzing the elongation of chromosomal telomeres in eukaryotic cell division and is particularly active in cancer cells

Examples of telomerase in a Sentence

Recent Examples on the Web Melanoma, an aggressive form of skin cancer, is highly dependent on telomerase to grow, and three-quarters of all melanomas acquire mutations in telomerase. Jonathan Alder, The Conversation, 10 Nov. 2022 Even more interesting is the fact that TPP1 is known to activate telomerase. Jonathan Alder, The Conversation, 10 Nov. 2022 The level of the enzyme telomerase went up by 30%. Kristen Rogers, CNN, 13 June 2022 So the molecular cause is exactly the same base pair change in a telomerase gene. Linda Marsa, Discover Magazine, 31 Aug. 2016 Reactivating an enzyme called telomerase reverses some signs of ageing in mice. Ed Yong, Discover Magazine, 4 Dec. 2010 Our discoveries of telomeres and telomerase open a Pandora’s box of difficult questions. Veronique Greenwood, Discover Magazine, 18 May 2011 In the 1990s, scientists at the Bay Area biotech company Geron Corporation mapped the human gene for telomerase. Megan Molteni, STAT, 3 May 2021 There were even indications that telomerase activity could predict treatment response. Simon Makin, Scientific American, 1 Apr. 2020

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'telomerase.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History

First Known Use

1988, in the meaning defined above

Time Traveler
The first known use of telomerase was in 1988

Dictionary Entries Near telomerase

Cite this Entry

“Telomerase.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/telomerase. Accessed 27 May. 2024.

Medical Definition

telomerase

noun
tel·​o·​me·​rase te-ˈlō-mə-ˌrās, -ˌrāz How to pronounce telomerase (audio)
: a DNA polymerase that is a ribonucleoprotein catalyzing the elongation of chromosomal telomeres in eukaryotic cell division and is particularly active in cancer cells

More from Merriam-Webster on telomerase

Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!