synaptic

adjective

syn·​ap·​tic sə-ˈnap-tik How to pronounce synaptic (audio)
1
: of or relating to a synapsis
2
: of or relating to a synapse
synaptically adverb

Examples of synaptic in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
This process is mainly thought to result from synaptic plasticity, or changes to the trillions of connections between neurons. Yasemin Saplakoglu, Quanta Magazine, 24 Apr. 2026 Practicing and learning new skills enhances and strengthens the connections between brain neurons, a process called synaptic plasticity, according to a 2017 report from The American Society for Cell Biology. Ashton Jackson, CNBC, 24 Apr. 2026 Importantly, research suggests that psilocin also alters the brain’s ability to strengthen or weaken neural connections, referred to as synaptic plasticity. Hollis Karoly, The Conversation, 9 Apr. 2026 The study adds to the literature showing that alcohol has detrimental effects on synaptic transmission, synaptic function, synaptic plasticity, and overall behavior by altering neurotransmitter release, receptor signaling, and gene expression in the brain. Christopher Gardner, Hartford Courant, 16 Mar. 2026 See All Example Sentences for synaptic

Word History

Etymology

New Latin synapsis

First Known Use

1895, in the meaning defined at sense 1

Time Traveler
The first known use of synaptic was in 1895

Cite this Entry

“Synaptic.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/synaptic. Accessed 1 May. 2026.

Medical Definition

synaptic

adjective
syn·​ap·​tic
si-ˈnap-tik, British also sī-
1
: of, relating to, or participating in synapsis
synaptic chromosomes
2
: of or relating to a synapse
synaptic transmission
synaptically adverb
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!

More from Merriam-Webster