sul·​fo·​nyl·​urea ˌsəl-fə-ˌnil-ˈyu̇r-ē-ə How to pronounce sulfonylurea (audio)
: any of several hypoglycemic compounds related to the sulfonamides and used in the oral treatment of diabetes

Examples of sulfonylurea in a Sentence

Recent Examples on the Web Researchers also examined the impact of other second-line diabetes medications on pregnancy, including sulfonylureas, DPP-4 inhibitors, and SGLT2 inhibitors. Korin Miller, Verywell Health, 25 Apr. 2024 While these drugs shouldn’t be taken alongside certain other diabetes medications, like insulin or sulfonylurea, none of the ingredients should react poorly with a COVID vaccine. Rachel Murphy, Verywell Health, 3 Nov. 2023 Patients typically take insulin, metformin, sulfonylureas or newer, more expensive medications, including SGLT2 inhibitors, to control their blood sugar. Sumathi Reddy, WSJ, 12 Mar. 2018

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'sulfonylurea.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History


New Latin, from International Scientific Vocabulary sulfonyl + New Latin urea

First Known Use

1956, in the meaning defined above

Time Traveler
The first known use of sulfonylurea was in 1956

Dictionary Entries Near sulfonylurea

Cite this Entry

“Sulfonylurea.” Dictionary, Merriam-Webster, Accessed 28 May. 2024.

Medical Definition


variants or chiefly British sulphonylurea
: any of several hypoglycemic compounds (as glipizide and tolbutamide) related to the sulfonamides and used in the oral treatment of type 2 diabetes

More from Merriam-Webster on sulfonylurea

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