sulfamethoxazole

noun

sul·​fa·​meth·​ox·​a·​zole ˌsəl-fə-ˌme-ˈthäk-sə-ˌzōl 

: an antibacterial sulfonamide C₁₀H₁₁N₃O₃S used alone or in combination with trimethoprim (as in the treatment of urinary tract infections or acute otitis media)

Examples of sulfamethoxazole in a Sentence

Recent Examples on the Web

Cyclospora can be treated with the combination antibiotic trimethoprim-sulfamethoxazole, also known as Bactrim, Septra or Cotrim. — Cindy Krischer Goodman, Sun Sentinel, 17 July 2026

Cyclosporiasis is treated with the oral antibiotic trimethoprim-sulfamethoxazole (TMP-SMX), commonly sold as Bactrim, Septra and Cotrim, and taken for 10 days, according to the CDC. — Mary Kekatos, ABC News, 13 July 2026

Treatment is seven to 10 days of the combination antibiotic sulfamethoxazole-trimethoprim, which is sold as Bactrim or Septra. — Brenda Goodman, CNN Money, 13 July 2026

Cyclosporiasis can be treated with a combination antibiotic, Trimethoprim-sulfamethoxazole. — Eva Flowe july 8, Charlotte Observer, 8 July 2026

Word History

Etymology

sulfa + methyl + oxazole, a compound C₃H₃NO (from International Scientific Vocabulary ox- + azole)

First Known Use

1960, in the meaning defined above

Rhymes for sulfamethoxazole

• benzimidazole
• dipyridamole
• itraconazole
• ketoconazole
• metronidazole
• sulfathiazole
• thiabendazole
• acholi
• emboli
• sertoli
• unholy
• carbazole

Medical Definition

sulfamethoxazole

noun

sul·​fa·​meth·​ox·​a·​zole

variants or chiefly British sulphamethoxazole

-ˌmeth-ˈäk-sə-ˌzōl 

: an antibacterial sulfonamide C₁₀H₁₁N₃O₃S used alone (as in the treatment of urinary tract infections or prophylaxis against meningococcal meningitis) or in combination with trimethoprim (as in the treatment of Pneumocystis carinii pneumonia, shigellosis, acute otitis media, or urinary tract infections) see bactrim, septra