subacute sclerosing panencephalitis

noun

subacute sclerosing pan·​en·​ceph·​a·​li·​tis -ˌpan-in-ˌse-fə-ˈlī-təs How to pronounce subacute sclerosing panencephalitis (audio)
: a usually fatal neurological disease of children and young adults caused by infection of the brain by a previously latent measles virus that is marked especially by behavioral changes, myoclonic seizures, progressive deterioration of motor and mental functioning, and coma

Examples of subacute sclerosing panencephalitis in a Sentence

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Measles can also cause a rare but fatal central nervous system condition called subacute sclerosing panencephalitis years after someone is initially exposed. Suzanne King, Kansas City Star, 19 May 2025 Another type, called subacute sclerosing panencephalitis (SSPE), is a degenerative condition that can occur up to a decade after a measles infection. Emily Baumgaertner Nunn, New York Times, 4 Apr. 2025 This condition, called subacute sclerosing panencephalitis, is a progressive dementia that is almost always fatal. Peter Kasson, The Conversation, 31 Mar. 2025 In addition to neurological and respiratory complications from measles infections, which can demonstrably turn deadly, measles can cause subacute sclerosing panencephalitis (SSPE), a fatal neurological condition that can flare seven to 10 years after a measles infection. Ars Technica, 20 Mar. 2025 Worried, the teen's parents took him to a series of doctors to figure out what was wrong, until a pediatric neurologist finally suspected a condition called subacute sclerosing panencephalitis, or SSPE. Maria Godoy, NPR, 17 Mar. 2025 The other big long-term complication that can happen after a measles infection is subacute sclerosing panencephalitis (SSPE). Bruce Y. Lee, Forbes, 15 Mar. 2025 Medical complications can include pneumonia, deafness, blindness, encephalitis (brain swelling) and subacute sclerosing panencephalitis, a progressive neurological disease. Jia H. Jung, The Mercury News, 11 Mar. 2025 Among people who contracted the measles during the U.S. outbreak in 1989-1991, seven to 11 of every 100,000 were estimated to be at risk for developing subacute sclerosing panencephalitis. USA TODAY, 26 Feb. 2025

Word History

Etymology

panencephalitis from New Latin, from pan- + encephalitis

First Known Use

1950, in the meaning defined above

Time Traveler
The first known use of subacute sclerosing panencephalitis was in 1950

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Cite this Entry

“Subacute sclerosing panencephalitis.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/subacute%20sclerosing%20panencephalitis. Accessed 29 May. 2025.

Medical Definition

subacute sclerosing panencephalitis

noun
: a usually fatal neurological disease of children and young adults that is caused by infection of the brain by a previously latent morbillivirus causing measles and that is marked especially by behavioral changes, myoclonic seizures, progressive deterioration of motor and mental functioning, and coma
abbreviation SSPE

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