subacute sclerosing panencephalitis

noun

subacute sclerosing pan·​en·​ceph·​a·​li·​tis -ˌpan-in-ˌse-fə-ˈlī-təs How to pronounce subacute sclerosing panencephalitis (audio)
: a usually fatal neurological disease of children and young adults caused by infection of the brain by a previously latent measles virus that is marked especially by behavioral changes, myoclonic seizures, progressive deterioration of motor and mental functioning, and coma

Examples of subacute sclerosing panencephalitis in a Sentence

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The child who died suffered from subacute sclerosing panencephalitis (SSPE), a progressive brain disorder that usually develops two to 10 years after a measles infection. Andrea Thompson, Scientific American, 12 Sep. 2025 Despite recovering from the original illness, the child ended up developing a rare disease called subacute sclerosing panencephalitis (SSPE), which caused their death. Gabrielle Rockson, PEOPLE, 12 Sep. 2025 Their death was due to subacute sclerosing panencephalitis (SSPE). Joseph Choi, The Hill, 12 Sep. 2025 Specifically, the child died of subacute sclerosing panencephalitis (SSPE), a rare, but always fatal complication that strikes years after an initial measles infection. Beth Mole, ArsTechnica, 11 Sep. 2025 The child recovered, but years later developed a rare, progressive brain disorder known as subacute sclerosing panencephalitis (SSPE), the department said. Aria Bendix, NBC news, 11 Sep. 2025 In rare cases, measles can also lead to subacute sclerosing panencephalitis (SSPE), a fatal brain disease that can appear seven to 10 years after someone has had measles. Lauryn Higgins, Flow Space, 15 July 2025 And years after contracting measles, people can later develop subacute sclerosing panencephalitis, or SSPE, a rare but fatal complication resulting from a weakened form of the virus remaining in the body, and later infecting the brain. Rong-Gong Lin Ii, Los Angeles Times, 26 June 2025

Word History

Etymology

panencephalitis from New Latin, from pan- + encephalitis

First Known Use

1950, in the meaning defined above

Time Traveler
The first known use of subacute sclerosing panencephalitis was in 1950

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Cite this Entry

“Subacute sclerosing panencephalitis.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/subacute%20sclerosing%20panencephalitis. Accessed 4 Oct. 2025.

Medical Definition

subacute sclerosing panencephalitis

noun
: a usually fatal neurological disease of children and young adults that is caused by infection of the brain by a previously latent morbillivirus causing measles and that is marked especially by behavioral changes, myoclonic seizures, progressive deterioration of motor and mental functioning, and coma
abbreviation SSPE

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