SSRI
noun
: any of a class of antidepressants (such as fluoxetine) that inhibit the inactivation of serotonin by blocking its reuptake by presynaptic neuron endings
called also selective serotonin reuptake inhibitor
Examples of SSRI in a Sentence
Recent Examples on the Web
Most were taking either a selective serotonin reuptake inhibitor (SSRI) or a serotonin and norepinephrine reuptake inhibitor (SNRI).
—
Emily Kay Votruba, EverydayHealth.com, 11 Dec. 2025
In the case of some drugs like selective serotonin reuptake inhibitor (SSRI) antidepressants, the medications may change the levels of neurotransmitters, such as serotonin, in the brain, which can affect dreams and nightmares.
—Stacey Colino, Time, 3 Nov. 2025
SNRIs are often seen as a second line of defense if SSRI treatment does not help, per NYU Langone.
—Hannah Yasharoff, USA Today, 6 Oct. 2025
Tuesday’s report states that HHS will assemble a working group of federal officials to evaluate SSRI prescribing patterns, specifically among children.
—Sarah Owermohle, CNN Money, 9 Sep. 2025
Emily Corwin is one of millions of people who has taken an SSRI.
—Emily Kwong, NPR, 2 Sep. 2025
It hasn’t been confirmed whether or not the shooter, who turned the gun on himself after the murders, was on an SSRI.
—Cara Lynn Shultz, People.com, 29 Aug. 2025
Multiple public-health researchers and clinicians have added that prior studies did not establish a causal link between SSRI use and mass shootings.
—Hannah Parry, MSNBC Newsweek, 28 Aug. 2025
Antidepressants: If needed, your healthcare provider may recommend taking a low dose of an antidepressant such as a selective serotonin reuptake inhibitor (SSRI).
—Carrie Madormo, Verywell Health, 12 Aug. 2025
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Emily Kay Votruba, EverydayHealth.com, 11 Dec. 2025
In the case of some drugs like selective serotonin reuptake inhibitor (SSRI) antidepressants, the medications may change the levels of neurotransmitters, such as serotonin, in the brain, which can affect dreams and nightmares.
—Stacey Colino, Time, 3 Nov. 2025
SNRIs are often seen as a second line of defense if SSRI treatment does not help, per NYU Langone.
—Hannah Yasharoff, USA Today, 6 Oct. 2025
Tuesday’s report states that HHS will assemble a working group of federal officials to evaluate SSRI prescribing patterns, specifically among children.
—Sarah Owermohle, CNN Money, 9 Sep. 2025
Emily Corwin is one of millions of people who has taken an SSRI.
—Emily Kwong, NPR, 2 Sep. 2025
It hasn’t been confirmed whether or not the shooter, who turned the gun on himself after the murders, was on an SSRI.
—Cara Lynn Shultz, People.com, 29 Aug. 2025
Multiple public-health researchers and clinicians have added that prior studies did not establish a causal link between SSRI use and mass shootings.
—Hannah Parry, MSNBC Newsweek, 28 Aug. 2025
Antidepressants: If needed, your healthcare provider may recommend taking a low dose of an antidepressant such as a selective serotonin reuptake inhibitor (SSRI).
—Carrie Madormo, Verywell Health, 12 Aug. 2025
Cite this Entry
“SSRI.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/SSRI. Accessed 20 Dec. 2025.
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SSRI
noun
: any of a class of antidepressants (as fluoxetine or sertraline) that inhibit the inactivation of serotonin by blocking its reuptake by presynaptic nerve cell endings
called also selective serotonin reuptake inhibitor
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