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                                                      : the waste piece on a casting (as of metal or plastic) left by the hole through which the mold was filled                                      
                
                    
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                                                      : the hole in which a sprue forms                                      
                
                    
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                                                      : a disease of tropical regions that is of unknown cause and is characterized by fatty diarrhea and malabsorption of nutrients                                      
                
called also tropical sprue
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  Merriam-Webster unabridged




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