significative

adjective
sig·​nif·​i·​ca·​tive | \ sig-ˈni-fə-ˌkā-tiv How to pronounce significative (audio) \

Definition of significative

2 : indicative symptoms significative of malaria

First Known Use of significative

1597, in the meaning defined at sense 2

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Time Traveler for significative

The first known use of significative was in 1597

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