side effect

noun

Synonyms of side effectnext
: a secondary and usually adverse effect (as of a drug)
toxic side effects

called also side reaction

Examples of side effect in a Sentence

Nausea and diarrhea are the side effects of the drug. the harmful side effects of using chemicals to kill insects The merger created positive side effects for both companies.
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
According to the website of Wegovy, another popular brand, the most common side effects include nausea, diarrhea, vomiting, constipation, abdominal pain, and headaches. Ayushi Shah, CNN Money, 8 Feb. 2026 Cagrilintide might also ease some of GLP-1 drugs’ common gastrointestinal side effects, such as severe nausea and vomiting, says Jesse Richards, an internal medicine and obesity clinician at the University of Oklahoma School of Community Medicine. Bethany Brookshire, Scientific American, 6 Feb. 2026 Some current obesity drugs have the side effect of losing muscle mass in addition to fat. Chris Hoffman, CBS News, 6 Feb. 2026 As early as 2017, a Pew Research study found that Black parents were less likely than white parents to see the health benefits of the MMR vaccine and more likely to consider the risks of potential side effects. Ej Dickson, Rolling Stone, 6 Feb. 2026 See All Example Sentences for side effect

Word History

First Known Use

1814, in the meaning defined above

Time Traveler
The first known use of side effect was in 1814

Browse Nearby Words

Cite this Entry

“Side effect.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/side%20effect. Accessed 8 Feb. 2026.

Kids Definition

side effect

noun
: an often harmful and unwanted effect (as of a drug) that occurs along with the basic desired effect
the environmental side effects of using chemicals to kill pests

Medical Definition

side effect

noun
: a secondary and usually adverse effect (as of a drug)
toxic side effects
a side effect of drowsiness caused by antihistamines

called also side reaction

Last Updated: - Updated example sentences
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