side effect

noun

: a secondary and usually adverse effect (as of a drug)
toxic side effects

called also side reaction

Examples of side effect in a Sentence

Nausea and diarrhea are the side effects of the drug. the harmful side effects of using chemicals to kill insects The merger created positive side effects for both companies.
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Many people experience side effects such as nausea, heartburn, diarrhea, and abdominal pain after surgery. Carrie Madormo, Health, 18 Oct. 2025 Concerns about finasteride's psychiatric side effects aren't new. Pranjal Malewar, New Atlas, 18 Oct. 2025 For consumers and companies, the positive climate outcomes are welcome side effects. Justin Worland, Time, 17 Oct. 2025 In men, it’s been associated with side effects like erectile dysfunction and decreased libido. Marci Robin, Allure, 17 Oct. 2025 See All Example Sentences for side effect

Word History

First Known Use

1814, in the meaning defined above

Time Traveler
The first known use of side effect was in 1814

Browse Nearby Words

Cite this Entry

“Side effect.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/side%20effect. Accessed 20 Oct. 2025.

Kids Definition

side effect

noun
: an often harmful and unwanted effect (as of a drug) that occurs along with the basic desired effect
the environmental side effects of using chemicals to kill pests

Medical Definition

side effect

noun
: a secondary and usually adverse effect (as of a drug)
toxic side effects
a side effect of drowsiness caused by antihistamines

called also side reaction

Last Updated: - Updated example sentences
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