side effect

noun

Synonyms of side effectnext
: a secondary and usually adverse effect (as of a drug)
toxic side effects

called also side reaction

Examples of side effect in a Sentence

Nausea and diarrhea are the side effects of the drug. the harmful side effects of using chemicals to kill insects The merger created positive side effects for both companies.
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Still, side effects such as nausea, vomiting and constipation were reported in more than 70% of those who took the higher dose of Wegovy, compared to more than 60% taking the lower dose and about 43% taking a dummy medication, the study showed. ABC News, 19 Mar. 2026 The most common side effects included headache, nausea, cough, fungal infection, and fatigue. Emily Kay Votruba, EverydayHealth.com, 19 Mar. 2026 Retatrutide has shown similar side effects, as well as a prickling sensation known as dysesthesia. Meg Tirrell, CNN Money, 19 Mar. 2026 The most common side effects among the trial group were nausea, diarrhea and vomiting. Jackie Flynn Mogensen, Scientific American, 19 Mar. 2026 See All Example Sentences for side effect

Word History

First Known Use

1814, in the meaning defined above

Time Traveler
The first known use of side effect was in 1814

Browse Nearby Words

Cite this Entry

“Side effect.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/side%20effect. Accessed 28 Mar. 2026.

Kids Definition

side effect

noun
: an often harmful and unwanted effect (as of a drug) that occurs along with the basic desired effect
the environmental side effects of using chemicals to kill pests

Medical Definition

side effect

noun
: a secondary and usually adverse effect (as of a drug)
toxic side effects
a side effect of drowsiness caused by antihistamines

called also side reaction

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