side effect

noun

Synonyms of side effectnext
: a secondary and usually adverse effect (as of a drug)
toxic side effects

called also side reaction

Examples of side effect in a Sentence

Nausea and diarrhea are the side effects of the drug. the harmful side effects of using chemicals to kill insects The merger created positive side effects for both companies.
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Physical side effects can include raised blood pressure and nausea. Natalia V. Osipova, CNN Money, 28 Mar. 2026 What are the side effects and weaknesses of mRNA vaccines? Meghan Bartels, Scientific American, 27 Mar. 2026 GLP-1s also have side effects such as nausea that might impact someone’s workout, Gary notes. Caitlin Carlson, SELF, 27 Mar. 2026 The effectiveness, safety, and side effects are similar to daily shots. Emily Kay Votruba, EverydayHealth.com, 27 Mar. 2026 See All Example Sentences for side effect

Word History

First Known Use

1814, in the meaning defined above

Time Traveler
The first known use of side effect was in 1814

Browse Nearby Words

Cite this Entry

“Side effect.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/side%20effect. Accessed 29 Mar. 2026.

Kids Definition

side effect

noun
: an often harmful and unwanted effect (as of a drug) that occurs along with the basic desired effect
the environmental side effects of using chemicals to kill pests

Medical Definition

side effect

noun
: a secondary and usually adverse effect (as of a drug)
toxic side effects
a side effect of drowsiness caused by antihistamines

called also side reaction

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