Synonyms of seminal
1
: of, relating to, or consisting of seed or semen
seminal discharge
2
: containing or contributing the seeds of later development : creative, original
a seminal book

Examples of seminal in a Sentence

Kandel was awarded the Nobel Prize in medicine in 2000 for his seminal observation that it was in the action of the synapses between cells that memory existed, not in the cells themselves, and that a molecule called cyclic AMP was what allowed cells to retain memory over the long term. Michael Greenberg, New York Review of Books, 4 Dec. 2008
Writer Susan Sontag died December 28 at age 71 after a long battle with cancer. She left behind an impressive body of fiction and criticism, including her seminal 1960s essays "Notes on Camp" and "Against Interpretation." Allan Gurganus, Advocate, 1 Feb. 2005
I wonder if the curators who organized "Matisse Picasso" ever asked themselves why it was that Alfred H. Barr Jr., the first director of the Museum of Modern Art and the guiding spirit behind the museum's seminal exhibitions of both Picasso and Matisse, never mounted a show like the one that has now arrived at MoMA QNS. Such an exhibition might seem to be logical, almost inevitable for the Museum of Modern Art. Jed Perl, New Republic, 3 Mar. 2003
Recent Examples on the Web
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In the seminal antitrust lawsuits brought by Ed O’Bannon, Shawne Alston and Grant House, more than a year — and sometimes four years— passed before certification. Michael McCann, Sportico.com, 1 Aug. 2026 Big Pussy was seminal to the show’s lore as Tony’s longtime best friend and trusted mob enforcer; his betrayal in becoming an FBI informant led to his murder and became one of the show’s most memorable scenes early in the show’s run. Senior Television, Los Angeles Times, 1 Aug. 2026 Celebrated jazzman Masekela, who was forced into exile following the 1960 Sharpeville Massacre for his anti-Apartheid activism, was a seminal figure in the struggle to repeal South Africa’s discriminatory racial segregation rules. Melanie Goodfellow, Deadline, 30 July 2026 The Beatles’ next release in their ongoing Super Deluxe series is their seminal 1965 album Rubber Soul. Alex Suskind, Pitchfork, 29 July 2026 See All Example Sentences for seminal

Word History

Etymology

Middle English, from Latin seminalis, from semin-, semen seed — more at semen

First Known Use

14th century, in the meaning defined at sense 1

Time Traveler
The first known use of seminal was in the 14th century

Cite this Entry

“Seminal.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/seminal. Accessed 4 Aug. 2026.

Medical Definition

seminal

adjective
: of, relating to, or consisting of seed or semen
seminal discharge

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