sedative

1 of 2

adjective

sed·​a·​tive ˈse-də-tiv 

: tending to calm, moderate, or tranquilize nervousness or excitement

sedative

2 of 2

noun

: a sedative agent or drug

Synonyms of sedative

Adjective

• relaxing
• tranquilizing
• soothing
• comforting
• hypnotic

Examples of sedative in a Sentence

Adjective

some people find a glass of wine to be a civilized and sedative addition to an evening meal

Noun

The patient was given a powerful sedative.

Recent Examples on the Web

Adjective

This ancient beverage, derived from the roots of the Piper methysticum plant, is typically consumed to produce sedative and euphoric effects that might increase sociability and reduce anxiety. —Bestreviews, Mercury News, 11 Feb. 2026

Unlike traditional sleep aids that rely on masking noise or sedative effects, Spatial Sleep is designed to work with the user’s neurobiology. —Soundhealth, New York Daily News, 16 Jan. 2026

Noun

Chamomile may interact with drugs that are metabolized by the liver, blood thinners, or sedatives. —Ann Pietrangelo, Verywell Health, 16 Feb. 2026

All Florida executions are carried out via lethal injection using a sedative, a paralytic and a drug that stops the heart, according to the Department of Corrections. —CBS News, 10 Feb. 2026

Word History

Etymology

Adjective

Middle English, alleviating pain, from Middle French sedatif, from Medieval Latin sedativus, from Latin sedatus

First Known Use

Adjective

1779, in the meaning defined above

Noun

1797, in the meaning defined above

Kids Definition

sedative

1 of 2 adjective

sed·​a·​tive ˈsed-ət-iv 

: tending to calm or to ease tension

sedative

2 of 2 noun

: a sedative medicine

Medical Definition

sedative

1 of 2 adjective

sed·​a·​tive ˈsed-ət-iv 

: tending to calm, moderate, or tranquilize nervousness or excitement

sedative effects of anesthetics and analgesics

—Linda C. Haynes et al.

sedative

2 of 2 noun

: a sedative agent or drug