sar·​co·​lem·​ma ˌsär-kə-ˈle-mə How to pronounce sarcolemma (audio)
: the membrane enclosing a striated muscle fiber
sarcolemmal adjective

Examples of sarcolemma in a Sentence

Recent Examples on the Web Curiously, the fungus destroyed the sarcolemma, a kind of sheath around the muscle fibers. Matt Simon, WIRED, 17 July 2019

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'sarcolemma.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History


sarco- + Greek lémma "rind, husk" — more at lemma entry 2

Note: Term introduced by the English surgeon and histologist William Bowman (1816-92) in "On the minute structure and movements of voluntary muscle," Philosophical Transactions of the Royal Society of London, 1840, part II, p. 475.

First Known Use

1840, in the meaning defined above

Time Traveler
The first known use of sarcolemma was in 1840

Dictionary Entries Near sarcolemma

Cite this Entry

“Sarcolemma.” Dictionary, Merriam-Webster, Accessed 15 Jul. 2024.

Medical Definition


sar·​co·​lem·​ma ˌsär-kə-ˈlem-ə How to pronounce sarcolemma (audio)
: the thin transparent homogeneous sheath enclosing a striated muscle fiber
sarcolemmal adjective

More from Merriam-Webster on sarcolemma

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