ritonavir

noun
ri·​to·​na·​vir | \ ˌrī-ˈtō-nə-ˌvir How to pronounce ritonavir (audio) , -ˈtä-, ri- \

Definition of ritonavir

: an antiviral protease inhibitor C37H48N6O5S2 administered orally to treat HIV infection and AIDS

Examples of ritonavir in a Sentence

Recent Examples on the Web Ongoing studies showed that Kaletra, a combination of the drugs lopinavir and ritonavir, gave little benefit, according to early results published Wednesday in the New England Journal of Medicine. John Lauerman, Bloomberg.com, "WHO Adopts Test Method That Helped Stifle Ebola for Coronavirus," 12 May 2020 Interferon 1-b has generally been used to treat multiple sclerosis in the past, while lopinavir-ritonavir and ribavirin have been used to treat HIV and hepatitis C, respectively. Fox News, "Drug trio shortens duration and alleviates coronavirus symptoms, study says," 11 May 2020 The confusion is understandable considering that two other medications used for H.I.V. — lopinavir and ritonavir, which act on the enzyme protease — have been investigated as treatment for Covid-19. New York Times, "Sex and the Coronavirus: Reader Questions, Answered," 10 Apr. 2020 Because lopinavir is quickly broken down in the human body by our own proteases, it is given with low levels of ritonavir, another protease inhibitor, that lets lopinavir persist longer. Jon Cohen, Science | AAAS, "WHO launches global megatrial of the four most promising coronavirus treatments," 22 Mar. 2020 Opinavir and ritonavir are a combination sold as one drug that’s used to treat HIV infections. Emily Bamforth, cleveland, "Coronavirus anti-viral update: 4 treatments included in WHO’s global trial," 28 Mar. 2020 Last week, the first major study to investigate a combination of HIV drugs, lopinavir and ritonavir, for use in coronavirus patients found no benefit. NBC News, "'Lives are on the line': Science matters in finding coronavirus treatments," 23 Mar. 2020 Doctors in Wuhan, China, gave 199 patients two pills of lopinavir/ritonavir twice a day plus standard care, or standard care alone. Jon Cohen, Science | AAAS, "WHO launches global megatrial of the four most promising coronavirus treatments," 22 Mar. 2020 The combination of lopinavir and ritonavir, marketed by AbbVie Inc. as Kaletra, didn’t improve the condition of severe Covid-19 patients or prevent them from dying more than standard care in a randomized, controlled trial of 199 patients. Jason Gale, Fortune, "HIV pill fails while flu medication helps in early coronavirus drug trials," 19 Mar. 2020

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'ritonavir.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of ritonavir

1995, in the meaning defined above

History and Etymology for ritonavir

rito- (perhaps by shortening & alteration from protease) + -navir (as in saquinavir)

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Time Traveler for ritonavir

Time Traveler

The first known use of ritonavir was in 1995

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Cite this Entry

“Ritonavir.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/ritonavir. Accessed 23 Jan. 2021.

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More Definitions for ritonavir

ritonavir

noun
ri·​to·​na·​vir | \ ˌrī-ˈtō-nə-ˌvir, -ˈtän-ə-, ri- How to pronounce ritonavir (audio) \

Medical Definition of ritonavir

: an antiviral protease inhibitor C37H48N6O5S2 administered orally to treat HIV infection and AIDS — see norvir

Comments on ritonavir

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